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「自閉スペクトラム症、腸内細菌のバイオマーカーで早期診断と予後予測へ前進」の検索結果

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("Autism Spectrum Disorder"[MeSH] OR ASD OR autism) AND ("Gastrointestinal Microbiome"[MeSH] OR "gut microbiota" OR "intestinal microbiome" OR "gut bacteria") AND (biomarker* OR "biological markers"[MeSH]) AND ("early diagnosis"[MeSH] OR "early detection" OR prognosis[MeSH] OR prediction)

💡 自閉スペクトラム症と腸内細菌叢のバイオマーカーによる早期診断・予後予測に関する包括的検索。同義語を含めて網羅性を確保。

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🔍 PubMed の検索結果

  • Double-edged sword effect of Sutterella in neurological disorders: implications for the gut-brain axis and neuroimmune interactions.

    Samin Davoody, Hossein Halimi, Alireza Zali 他 · Neurobiology of disease · 2025

    The genus Sutterella, a group of bile-resistant microaerophilic gram-negative bacteria, has emerged as a key player in gut-brain axis communication, with significant yet complex implications for neurological and psychiatric disorders. This study synthesizes current evidence on Sutterella's dual role in modulating immune responses and neuroinflammation, highlighting its context-dependent effects ac…

    📄 PubMed で読む (PMID: 40681117)
  • Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015) : Jeddah, Kingdom of Saudi Arabia. 30 November - 3 December 2015.

    Jerry W. Shay, Noriko Homma, Ruyun Zhou 他 · BMC genomics · 2016

    O1 Regulation of genes by telomere length over long distances Jerry W. Shay O2 The microtubule destabilizer KIF2A regulates the postnatal establishment of neuronal circuits in addition to prenatal cell survival, cell migration, and axon elongation, and its loss leading to malformation of cortical development and severe epilepsy Noriko Homma, Ruyun Zhou, Muhammad Imran Naseer, Adeel G. Chaudhary, M…

    📄 PubMed で読む (PMID: 27454254)
  • Microbiome biomarkers in autism spectrum disorder: Toward prediction, diagnosis, and prognosis.

    Oscar Wong, Zhijie Zheng, Mingbang Wang 他 · Cell reports. Medicine · 2026

    Autism spectrum disorder (ASD) is a heterogeneous condition that lacks objective diagnostic biomarkers, often resulting in delayed intervention. Evidence increasingly links gut microbiota dysregulation to ASD pathophysiology via the microbiota-gut-brain axis, suggesting plausible translational applications. This review outlines mechanistic insights from preclinical and clinical studies to illustra…

    📄 PubMed で読む (PMID: 42049031)
  • Dietary and complementary oral supplements for the management of chronic diseases in children: a systematic review.

    Alessio Danilo Inchingolo, Grazia Marinelli, Luisa Limongelli 他 · Frontiers in pediatrics · 2025

    Chronic diseases in childhood and adolescence represent a growing global challenge, with families often seeking complementary strategies beyond pharmacological treatment. This systematic review aimed to evaluate the efficacy and safety of dietary and oral supplements in pediatric chronic diseases. The review was conducted in accordance with PRISMA guidelines. A systematic search of PubMed, Scopus,…

    📄 PubMed で読む (PMID: 41613379)
  • Kefir-derived probiotic mixture for children with autism spectrum disorder: a double-blind randomized clinical trial.

    Sarha A L de Queiroz, Deivis O Guimarães, Lara A Ferreira 他 · BMC pediatrics · 2026

    PURPOSE: Emerging evidence suggests associations between gut microbiota patterns and autism-related behavioral and gastrointestinal features, increasing interest in probiotic interventions. This trial aimed to evaluate the effects of kefir-derived probiotics (K11 and K11-TMAX) on adaptive functioning, autism-related traits, and inflammatory/metabolic markers in children with Autism Spectrum Disord…

    📄 PubMed で読む (PMID: 41547752)
  • Predicting autism spectrum disorder through the gut microbiota composition using machine learning.

    Dejun Li, Ziyu Huang, Ailing Wei 他 · Bioscience of microbiota, food and health · 2026

    The human gut microbiota plays a crucial role in overall health, impacting various diseases, including autism spectrum disorder (ASD). This study explores the relationship between gut microbiota changes and ASD by analyzing microbial compositions and abundances of 692 gut microbiota samples using public 16S rRNA sequencing datasets. Data preprocessing included normalization and redundancy reductio…

    📄 PubMed で読む (PMID: 41492373)
  • In-silico assessment of dynamic symbiotic microbial interactions in a reduced microbiota related to the autism spectrum disorder symptoms.

    Juan Manuel Olaguez-Gonzalez, Isaac Chairez, Luz Breton-Deval 他 · Computational and structural biotechnology journal · 2025

    The gut microbiota plays a crucial role in human health, with growing evidence linking its composition to the development of Autism Spectrum Disorder. However, inconsistencies in previous studies have hindered the identification of a definitive microbial signature associated with Autism Spectrum Disorder. Machine learning models have emerged as powerful tools for analyzing microbiome data, yet the…

    📄 PubMed で読む (PMID: 41035504)
  • The Significance of Serum Immunoglobulin Concentrations in Children with Autism Spectrum Disorders: In Search of Potential Blood Biomarkers.

    Joanna Wawer, Agnieszka Chojęta, Genowefa Anna Wawer 他 · International journal of molecular sciences · 2025

    Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental disorders characterized by a number of dysfunctions in communication, social interactions and repetitive rigid patterns of behavior, interests, and activities. Despite much research, the causes of ASD remain elusive. In addition to genetic and epigenetic etiology, scientists have indicated inflammation, deregulation of…

    📄 PubMed で読む (PMID: 41009802)
  • Understanding autism: Causes, diagnosis, and advancing therapies.

    Min Wang, Xiaozhuang Zhang, Liyan Zhong 他 · Brain research bulletin · 2025

    Autism Spectrum Disorder (ASD) is a neurodevelopmental condition marked by difficulties in social communication, languages, and repetitive behaviors. Its rising prevalence has made it a critical global public health issue. ASD is believed to arise from a combination of genetic and environmental influences. While some gene mutations associated with ASD have been identified, most cases lack clear ge…

    📄 PubMed で読む (PMID: 40449388)
  • Fecal microbial marker panel for aiding diagnosis of autism spectrum disorders.

    Yating Wan, Oscar W H Wong, Hein M Tun 他 · Gut microbes · 2024

    Accumulating evidence suggests that gut microbiota alterations influence brain function and could serve as diagnostic biomarkers and therapeutic targets. The potential of using fecal microbiota signatures to aid autism spectrum disorder (ASD) detection is still not fully explored. Here, we assessed the potential of different levels of microbial markers (taxonomy and genome) in distinguishing child…

    📄 PubMed で読む (PMID: 39468837)