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「敗血症性心筋症と腸内細菌の双方向ネットワーク」の検索結果

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("septic cardiomyopathy"[Title/Abstract] OR (sepsis[MeSH] AND (cardiomyopathy[MeSH] OR "myocardial dysfunction"[Title/Abstract]))) AND ("gut microbiota"[MeSH] OR "gut microbiome"[Title/Abstract] OR "intestinal flora"[Title/Abstract] OR "gut-heart axis"[Title/Abstract])

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🔍 PubMed の検索結果

  • Cholinergic drugs reduce metabolic inflammation and diabetic myocardial injury by regulating the gut bacterial component lipopolysaccharide-induced ERK/Egr-1 pathway.

    Qing Wu, Ming Zhao, Dongling Li 他 · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2023

    Autonomic imbalance and metabolic inflammation are important pathological processes in diabetic cardiomyopathy. Gut microbiota dysbiosis and increased levels of bacterial component lipopolysaccharide (LPS) are associated with diabetic myocardial injury, but the mechanism by which gut microbes affect metabolic inflammation and cardiac injury remains unclear. We determined whether pyridostigmine (PY…

    📄 PubMed で読む (PMID: 37039813)

  • Gut microbiota and serum metabolic profiles in patients with sepsis-induced cardiomyopathy and their association with the disease.

    Kai Chen, Jia Lin, Yizhuo Zhang 他 · Frontiers in cellular and infection microbiology · 2026

    The pathogenesis of sepsis-induced cardiomyopathy (SIC) remains unclear, and the lack of effective treatment options results in high mortality rates. There may be interactions between gut microbiota dysbiosis, serum metabolic changes, and SIC; however, research in this area is limited. This study aims to provide a theoretical basis for targeted interventions to improve the gut microbiome, thereby …

    📄 PubMed で読む (PMID: 42499545)

  • Interaction between gut-heart axis in sepsis-induced cardiomyopathy.

    Zi-Kang Zhou, Mu-Ming Yu, Song-Tao Shou 他 · Pharmacological research · 2025

    The gut microbiota and its metabolites profoundly influence cardiac function, emerging as critical players in the pathophysiology of Sepsis-Induced Cardiomyopathy (SIC). Conversely, therapeutic interventions for SIC and the resultant cardiac alterations can reciprocally modulate gut microbial composition and function. To systematically elucidate this complex bidirectional relationship during SIC, …

    📄 PubMed で読む (PMID: 40449812)

  • Gut microbiota dysbiosis is associated with sepsis-induced cardiomyopathy in patients: A case-control study.

    Fan Deng, Yu Chen, Qi-Shun Sun 他 · Journal of medical virology · 2023

    Myocardial injury is a major complication of sepsis and a key factor affecting prognosis. Therefore, early and accurate diagnosis and timely management of sepsis-induced cardiomyopathy (SICM) are of great significance for the prevention and treatment of sepsis. The gut microbiota has been shown to be closely associated with sepsis or myocardial injury, but the association between the gut microbiot…

    📄 PubMed で読む (PMID: 36319439)
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