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「幼少期逆境体験が脳に刻む2つの神経パターン」の検索結果

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("adverse childhood experiences"[MeSH] OR ACE OR "childhood adversity" OR "early life stress") AND (brain[MeSH] OR neural OR neurobiological) AND (pattern OR pathway OR circuit OR mechanism)

💡 幼少期逆境体験(ACE)と脳の神経パターンの関連を検索。MeSHterm と同義語を組み合わせて網羅性を確保しました。

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  • Editorial.

    Siegfried Kasper · The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2019

    📄 PubMed で読む (PMID: 31145038)
  • Neurobiology of emotional trauma.

    O Giotakos · Psychiatrike = Psychiatriki · 2020

    An emotional trauma may induce a cascade of neurobiological events that have long-lasting consequences even altered gene expression. Early abuse and neglect can deregulate the child's developing neurobiological system by reducing its resistance to stressful events, leading to later problems of emotional regulation. Children who have been subjected to physical or emotional abuse tend to pay more at…

    📄 PubMed で読む (PMID: 32840220)
  • The evolving neurobiology of early-life stress.

    Matthew T Birnie, Tallie Z Baram · Neuron · 2025

    Because early-life stress is common and constitutes a strong risk factor for cognitive and mental health disorders, it has been the focus of a multitude of studies in humans and experimental models. Yet, we have an incomplete understanding of what is perceived as stressful by the developing brain, what aspects of stress influence brain maturation, what developmental ages are particularly vulnerabl…

    📄 PubMed で読む (PMID: 40101719)
  • The Role of Early Life Stress in HPA Axis and Anxiety.

    Mario F Juruena, Filip Eror, Anthony J Cleare 他 · Advances in experimental medicine and biology · 2020

    Substantial evidence from various studies suggests a preeminent role for early adverse experiences in the development of psychopathology. The most recent studies reviewed here suggest that early life stressors are associated with an increased risk for anxiety disorders in adulthood. Early life stress predisposes individuals to develop a number of psychiatric syndromes, particularly affective disor…

    📄 PubMed で読む (PMID: 32002927)
  • Stress and the social brain: behavioural effects and neurobiological mechanisms.

    Carmen Sandi, József Haller · Nature reviews. Neuroscience · 2015

    Stress often affects our social lives. When undergoing high-level or persistent stress, individuals frequently retract from social interactions and become irritable and hostile. Predisposition to antisocial behaviours - including social detachment and violence - is also modulated by early life adversity; however, the effects of early life stress depend on the timing of exposure and genetic factors…

    📄 PubMed で読む (PMID: 25891510)
  • Early life stress and development: potential mechanisms for adverse outcomes.

    Karen E Smith, Seth D Pollak · Journal of neurodevelopmental disorders · 2020

    Chronic and/or extreme stress in early life, often referred to as early adversity, childhood trauma, or early life stress, has been associated with a wide range of adverse effects on development. However, while early life stress has been linked to negative effects on a number of neural systems, the specific mechanisms through which early life stress influences development and individual difference…

    📄 PubMed で読む (PMID: 33327939)
  • Executive Function and Psychopathology: A Neurodevelopmental Perspective.

    Philip David Zelazo · Annual review of clinical psychology · 2020

    Executive function (EF) skills are neurocognitive skills that support the reflective, top-down coordination and control of other brain functions, and there is neural and behavioral evidence for a continuum from more "cool" EF skills activated in emotionally neutral contexts to more "hot" EF skills needed for the reversal of motivationally significant tendencies. Difficulties in EF are transdiagnos…

    📄 PubMed で読む (PMID: 32075434)
  • Behavioral processes and risk for problem substance use in adolescents.

    Ashley Acheson · Pharmacology, biochemistry, and behavior · 2020

    This narrative review examines associations of delay discounting, response inhibition, sensation-seeking, and urgency with adolescent problem substance use. Each of these processes is linked to adult substance use disorders, is associated with conditions linked to increased risk for adolescent problem substance use, and predicts problem substance use. Notably, all processes are linked to early lif…

    📄 PubMed で読む (PMID: 32871140)
  • Neurobiology of resilience to early life stress.

    Angélica Torres-Berrío, Alessandro Bortolami, Catherine J Peña 他 · Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026

    The early years of life are a critical period for brain development, encompassing high sensitivity to adverse experiences. Early life stress (ELS) is known to "scar" the brain and shape mental health trajectories later in life. Still, a great percentage of children faced with ELS develop adaptive competencies that maintain normal physiological and behavioral function across the lifespan, a process…

    📄 PubMed で読む (PMID: 40562842)
  • The effect of adverse childhood experiences on chronic pain and major depression in adulthood: a systematic review and meta-analysis.

    Georgia Antoniou, Emilie Lambourg, J Douglas Steele 他 · British journal of anaesthesia · 2023

    Adverse childhood experiences have been linked to increased multimorbidity, with physical and mental health consequences throughout life. Chronic pain is often associated with mood disorders, such as major depressive disorder (MDD); both have been linked to adverse childhood experiences. It is unclear how the effect of adverse childhood experiences on neural processing impacts on vulnerability to …

    📄 PubMed で読む (PMID: 37087334)