Home › 🔬 PubMed Lab

🔬 PubMed Lab Free · No signup

Search PubMed with a plain-English research question, then chat with an AI about any paper. Powered by Claude (Anthropic) + NIH PubMed E-utilities.

10 of ~75 matches · 549 ms

  1. #1 JAMA psychiatry (2021)

    Perturbations in Gut Microbiota Composition in Psychiatric Disorders: A Review and Meta-analysis.

    Viktoriya L Nikolova, Megan R B Smith, Lindsay J Hall et al.

    Evidence of gut microbiota perturbations has accumulated for multiple psychiatric disorders, with microbiota signatures proposed as potential biomarkers. However, no attempts have been made to evaluate the specificity of these across the range of psychiatric conditions. To conduct an umbrella and updated meta-analysis of gut microbiota alterations in general adult psychiatric populations and perfo…

    🔗 Open on PubMed
  2. #2 BMJ (Clinical research ed.) (2024)

    Ultra-processed food exposure and adverse health outcomes: umbrella review of epidemiological meta-analyses.

    Melissa M Lane, Elizabeth Gamage, Shutong Du et al.

    To evaluate the existing meta-analytic evidence of associations between exposure to ultra-processed foods, as defined by the Nova food classification system, and adverse health outcomes. Systematic umbrella review of existing meta-analyses. MEDLINE, PsycINFO, Embase, and the Cochrane Database of Systematic Reviews, as well as manual searches of reference lists from 2009 to June 2023. Systematic re…

    🔗 Open on PubMed
  3. #3 Nutrition reviews (2025)

    Effects of Prebiotics and Probiotics on Symptoms of Depression and Anxiety in Clinically Diagnosed Samples: Systematic Review and Meta-analysis of Randomized Controlled Trials.

    Afrida Asad, Megan Kirk, Sufen Zhu et al.

    The use of prebiotics and probiotics as a treatment for psychiatric conditions has gained interest due to their potential to modulate the gut-brain axis. This review aims to assess the effectiveness of these interventions in reducing symptoms of depression and anxiety in psychiatric populations. The aim was to comprehensively review and appraise the effectiveness of prebiotic, probiotic, and synbi…

    🔗 Open on PubMed
  4. #4 Neuroscience and biobehavioral reviews (2019)

    Prebiotics and probiotics for depression and anxiety: A systematic review and meta-analysis of controlled clinical trials.

    Richard T Liu, Rachel F L Walsh, Ana E Sheehan et al.

    With growing interest in the gut microbiome, prebiotics and probiotics have received considerable attention as potential treatments for depression and anxiety. We conducted a random-effects meta-analysis of 34 controlled clinical trials evaluating the effects of prebiotics and probiotics on depression and anxiety. Prebiotics did not differ from placebo for depression (d = -.08, p = .51) or anxiety…

    🔗 Open on PubMed
  5. #5 Journal of affective disorders (2020)

    Gut microbiota and major depressive disorder: A systematic review and meta-analysis.

    Kenji Sanada, Shinichiro Nakajima, Shunya Kurokawa et al.

    Growing attention has been paid to the field of gut microbiota for mental disorders over the last decade. However, to our knowledge, no studies have conducted systematic reviews on the association between gut microbiota and major depressive disorder (MDD) in both interventional and non-interventional studies. We conducted a systematic review and meta-analysis of 16 studies (10 observational [701 p…

    🔗 Open on PubMed
  6. #6 Translational psychiatry (2023)

    Gut microbiota composition in depressive disorder: a systematic review, meta-analysis, and meta-regression.

    Mingxue Gao, Jizhi Wang, Penghong Liu et al.

    Studies investigating gut microbiota composition in depressive disorder have yielded mixed results. The aim of our study was to compare gut microbiome between people with depressive disorder and healthy controls. We did a meta-analysis and meta-regression of studies by searching PubMed, Web of Science, Embase, Scopus, Ovid, Cochrane Library, ProQuest, and PsycINFO for articles published from datab…

    🔗 Open on PubMed
  7. #7 Journal of psychosomatic obstetrics and gynaecology (2025)

    Meta-analysis of the association between gut microbiota and postpartum depression.

    Yan Guo, Wangxiang Chen

    This study aimed to explore the association between gut microbiota and postpartum depression (PPD) through meta-analysis, providing a basis for effective clinical preventive interventions.​. Systematic searches were conducted in English databases (Cochrane Library, Embase, Web of Science, PubMed) for studies published up to April 2025. Literature screening used a double-blind method, and quality a…

    🔗 Open on PubMed
  8. #8 Nutrition reviews (2024)

    Fiber intake and fiber intervention in depression and anxiety: a systematic review and meta-analysis of observational studies and randomized controlled trials.

    Hajara Aslam, Mojtaba Lotfaliany, Daniel So et al.

    Dietary fibers hold potential to influence depressive and anxiety outcomes by modulating the microbiota-gut-brain axis, which is increasingly recognized as an underlying factor in mental health maintenance. Evidence for the effects of fibers on depressive and anxiety outcomes remains unclear. To this end, a systematic literature review and a meta-analysis were conducted that included observational…

    🔗 Open on PubMed
  9. #9 European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology (2019)

    Nutritional psychiatry: Towards improving mental health by what you eat.

    Roger A H Adan, Eline M van der Beek, Jan K Buitelaar et al.

    Does it matter what we eat for our mental health? Accumulating data suggests that this may indeed be the case and that diet and nutrition are not only critical for human physiology and body composition, but also have significant effects on mood and mental wellbeing. While the determining factors of mental health are complex, increasing evidence indicates a strong association between a poor diet an…

    🔗 Open on PubMed
  10. #10 Brain and behavior (2025)

    The Effect of Prebiotics and Probiotics on Levels of Depression, Anxiety, and Cognitive Function: A Meta-Analysis of Randomized Clinical Trials.

    Atefeh Zandifar, Rahim Badrfam, Mahdi Mohammaditabar et al.

    Recent studies have emphasized the relationship between mental health and the human intestine microbiota. In this study, we evaluate the effect of consuming Biotics, on levels of depression, anxiety, and cognitive function. This meta-analysis adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) standards. We searched MEDLINE (PubMed), Cochrane Library, Scopus,…

    🔗 Open on PubMed

❓ How it works

What does this do?

You type a research question in English. We query the NIH PubMed database and show the top 10 most relevant. Click "💬 Chat with AI" below any paper to ask questions about its methods, findings, and limitations — inline, right below the paper.

Is this free?

Yes, and no signup is required. Funded by affiliate links + ads elsewhere on the site.

Any usage limit?

3 chat messages per browser per day (cost control). Search itself is unlimited.

Do you store my queries?

Queries appear in server logs (retained ~14 days for abuse prevention) and are sent to Anthropic's Claude API for chat (Anthropic's terms apply). Not sold to third parties.

Medical disclaimer?

The AI answers are general education, not medical advice. Consult a qualified professional for any health decision. See our editorial policy.