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Search PubMed with a plain-English research question, then chat with an AI about any paper. Powered by Claude (Anthropic) + NIH PubMed E-utilities.
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Mild Cognitive Impairment in Clinical Practice: A Review Article.
The spectrum of cognitive decline in the elderly ranges from what can be classified as normal cognitive decline with aging to subjective cognitive impairment to mild cognitive impairment (MCI) to dementia. This article reviewed the up-to-date evidence of MCI including the diagnostic criteria of MCI due to Alzheimer's disease, vascular cognitive impairment and MCI due to Parkinson disease, manageme…
💬 Chat with AI about this paper (β) Remaining 3 / 3 todayAnswers use only the paper's abstract. Not medical advice. Missing info returns "not stated in abstract."Question examples: "Summarize the 3 key findings" · "Limitations?" · "N and statistical method?" · "Possible counter-argument?"
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Effects of Mindfulness Training and Exercise on Cognitive Function in Older Adults: A Randomized Clinical Trial.
Episodic memory and executive function are essential aspects of cognitive functioning that decline with aging. This decline may be ameliorable with lifestyle interventions. To determine whether mindfulness-based stress reduction (MBSR), exercise, or a combination of both improve cognitive function in older adults. This 2 × 2 factorial randomized clinical trial was conducted at 2 US sites (Washingt…
💬 Chat with AI about this paper (β) Remaining 3 / 3 todayAnswers use only the paper's abstract. Not medical advice. Missing info returns "not stated in abstract."Question examples: "Summarize the 3 key findings" · "Limitations?" · "N and statistical method?" · "Possible counter-argument?"
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Nutrition, Physical Activity, and Other Lifestyle Factors in the Prevention of Cognitive Decline and Dementia.
Multiple factors combined are currently recognized as contributors to cognitive decline. The main independent risk factor for cognitive impairment and dementia is advanced age followed by other determinants such as genetic, socioeconomic, and environmental factors, including nutrition and physical activity. In the next decades, a rise in dementia cases is expected due largely to the aging of the w…
💬 Chat with AI about this paper (β) Remaining 3 / 3 todayAnswers use only the paper's abstract. Not medical advice. Missing info returns "not stated in abstract."Question examples: "Summarize the 3 key findings" · "Limitations?" · "N and statistical method?" · "Possible counter-argument?"
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Comparative efficacy of various exercise interventions on cognitive function in patients with mild cognitive impairment or dementia: A systematic review and network meta-analysis.
Exercise is a promising nonpharmacological therapy for cognitive dysfunction, but it is unclear which type of exercise is most effective. The objective of this study was to compare and rank the effectiveness of various exercise interventions on cognitive function in patients with mild cognitive impairment (MCI) or dementia and to examine the effects of exercise on the symptoms relevant to cognitiv…
💬 Chat with AI about this paper (β) Remaining 3 / 3 todayAnswers use only the paper's abstract. Not medical advice. Missing info returns "not stated in abstract."Question examples: "Summarize the 3 key findings" · "Limitations?" · "N and statistical method?" · "Possible counter-argument?"
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Cognitive rehabilitation and aerobic exercise for cognitive impairment in people with progressive multiple sclerosis (CogEx): a randomised, blinded, sham-controlled trial.
Cognitive dysfunction in people with relapsing-remitting multiple sclerosis can improve with cognitive rehabilitation or exercise. Similar effects have not been clearly shown in people with progressive multiple sclerosis. We aimed to investigate the individual and synergistic effects of cognitive rehabilitation and exercise in patients with progressive multiple sclerosis. CogEx was a randomised, s…
💬 Chat with AI about this paper (β) Remaining 3 / 3 todayAnswers use only the paper's abstract. Not medical advice. Missing info returns "not stated in abstract."Question examples: "Summarize the 3 key findings" · "Limitations?" · "N and statistical method?" · "Possible counter-argument?"
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Exercise to prevent falls in older adults: an updated systematic review and meta-analysis.
Previous meta-analyses have found that exercise prevents falls in older people. This study aimed to test whether this effect is still present when new trials are added, and it explores whether characteristics of the trial design, sample or intervention are associated with greater fall prevention effects. Update of a systematic review with random effects meta-analysis and meta-regression. Cochrane …
💬 Chat with AI about this paper (β) Remaining 3 / 3 todayAnswers use only the paper's abstract. Not medical advice. Missing info returns "not stated in abstract."Question examples: "Summarize the 3 key findings" · "Limitations?" · "N and statistical method?" · "Possible counter-argument?"
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Isometric exercise induces analgesia and reduces inhibition in patellar tendinopathy.
Few interventions reduce patellar tendinopathy (PT) pain in the short term. Eccentric exercises are painful and have limited effectiveness during the competitive season. Isometric and isotonic muscle contractions may have an immediate effect on PT pain. This single-blinded, randomised cross-over study compared immediate and 45 min effects following a bout of isometric and isotonic muscle contracti…
💬 Chat with AI about this paper (β) Remaining 3 / 3 todayAnswers use only the paper's abstract. Not medical advice. Missing info returns "not stated in abstract."Question examples: "Summarize the 3 key findings" · "Limitations?" · "N and statistical method?" · "Possible counter-argument?"
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A best practice fall prevention exercise program to improve balance, strength / power, and psychosocial health in older adults: study protocol for a randomized controlled trial.
With increasing age neuromuscular deficits (e.g., sarcopenia) may result in impaired physical performance and an increased risk for falls. Prominent intrinsic fall-risk factors are age-related decreases in balance and strength / power performance as well as cognitive decline. Additional studies are needed to develop specifically tailored exercise programs for older adults that can easily be implem…
💬 Chat with AI about this paper (β) Remaining 3 / 3 todayAnswers use only the paper's abstract. Not medical advice. Missing info returns "not stated in abstract."Question examples: "Summarize the 3 key findings" · "Limitations?" · "N and statistical method?" · "Possible counter-argument?"
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Neuroprotective mechanisms of exercise and the importance of fitness for healthy brain ageing.
Ageing is a scientifically fascinating and complex biological occurrence characterised by morphological and functional changes due to accumulated molecular and cellular damage impairing tissue and organ function. Ageing is often accompanied by cognitive decline but is also the biggest known risk factor for Alzheimer's disease, the most common form of dementia. Emerging evidence suggests that seden…
💬 Chat with AI about this paper (β) Remaining 3 / 3 todayAnswers use only the paper's abstract. Not medical advice. Missing info returns "not stated in abstract."Question examples: "Summarize the 3 key findings" · "Limitations?" · "N and statistical method?" · "Possible counter-argument?"
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Single-domain and multidomain lifestyle interventions for the prevention of cognitive decline in older adults who are cognitively unimpaired: a systematic review and network meta-analysis.
Preventing cognitive impairment in older adults is a public health priority. Although multidomain interventions have shown promise as preventive strategies, the optimal combination of interventions remains unclear. This network meta-analysis aimed to compare and rank the relative efficacy of single-domain and multidomain lifestyle interventions for the prevention of cognitive impairment in older a…
💬 Chat with AI about this paper (β) Remaining 3 / 3 todayAnswers use only the paper's abstract. Not medical advice. Missing info returns "not stated in abstract."Question examples: "Summarize the 3 key findings" · "Limitations?" · "N and statistical method?" · "Possible counter-argument?"
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